| 冷应激前后不同硒营养状态下大鼠甲状腺激素水平变化 |
| |
| 引用本文： | 呙于明,John R.Arthur,周毓平.冷应激前后不同硒营养状态下大鼠甲状腺激素水平变化[J].中国农业大学学报,1992(4):447-452. |
| |
| 作者姓名： | 呙于明 John R.Arthur 周毓平 |
| |
| 作者单位： | 北京农业大学;英国Rowett 研究所; |
| |
| 摘 要： | 大鼠硒耗竭6周后,其肝、肾、全血、褐脂肪、垂体等组织的谷胱甘肽过氧化物酶(GPX)及5′-脱碘酶活性极显著大幅度下降,而肝肾谷胱甘肽硫转移酶(GST)活性升高了。各组织 GPX及 GST 酶活性不受冷应激的影响;急促冷应激导致大鼠血浆中四碘甲腺原氨酸(T_4)、三碘甲腺原氨酸(T_3)和促甲状腺激素(TSH)的水平升高。大鼠在硒缺乏状态下,其 T_4,TSH 的上升幅度更大,而 T_3的上升幅度略小。冷应激不影响肝、肾及垂体等组织的5′-脱碘酶活性,只是脑组织的5′-脱碘酶活性略有下降,肩胛间褐脂肪组织重量和5′-脱碘活性分别显著大幅度下降和升高,硒营养缺乏明显减小其变化的幅度,说明硒缺乏会破坏大鼠的非寒颤性产热功能。
|
| 关 键 词： | 硒 冷应激 甲状腺激素 促甲状腺激素 5′-脱硒酶 褐脂肪 |
| 收稿时间： | 1992/2/22 0:00:00 |
Thyroid Hormone Metabolic Levels of Rats,under Different Selenim Nutritional Status,before and after Acute Cold Exposure |
| |
| Guo Yuming Zhou Yuping Beijing Agricultural University,Chin,John R.Arthur Rowett Research Institute.UK.Thyroid Hormone Metabolic Levels of Rats,under Different Selenim Nutritional Status,before and after Acute Cold Exposure[J].Journal of China Agricultural University,1992(4):447-452. |
| |
| Authors: | Guo Yuming Zhou Yuping Beijing Agricultural University Chin John RArthur Rowett Research InstituteUK |
| |
| Abstract: | After six weeks of selenium depletion,the glutathione peroxidase(GPX)and 5'-deiodinase activities of rat liver,kidney,blood,brown adipose tissue(BAT)and pituitary were much lowered significantly;but the liver and kidney glutathione S-transferase activities were elevated.The activities of GPX and GST were not influened by cold stress.Rats' plasma thyroxine and Thyrotropin level were significantly much elevated after acute cold exposure. and the magnitude of elevation of thyroxine and thyrotropin was greater ... |
| |
| Keywords: | selenium cold stress thyroid hormones thyrotropin 5'-deiodinase brown adipose tissue |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国农业大学学报》浏览原始摘要信息 |
| 点击此处可从《中国农业大学学报》下载免费的PDF全文 |
|
