| 水牛初乳粉对新生仔猪肠道黏膜和肝脏IGF-I及IGF-IR基因表达的影响 |
| |
| 引用本文： | 陈瑞芳,耿丹,郭傲民,张海燕,王士长.水牛初乳粉对新生仔猪肠道黏膜和肝脏IGF-I及IGF-IR基因表达的影响[J].山西农业大学学报(自然科学版),2013(6):526-530,552. |
| |
| 作者姓名： | 陈瑞芳 耿丹 郭傲民 张海燕 王士长 |
| |
| 作者单位： | [1]晋中职业技术学院生物技术系,山西榆次030600 [2]广西大学动物科学技术学院,广西南宁530004 |
| |
| 基金项目： | 广西科学研究与技术开发计划项目（桂科转0718005-5B） |
| |
| 摘 要： | 水牛初乳富含免疫球蛋白和生长因子等活性物质,对新生哺乳动物具有良好的营养作用.选用新生仔猪为试验对象,分别饲喂水牛初乳粉（SCR组）、水牛常乳粉（SC组）、葡萄糖盐水（PY组）,并以0日龄新生仔猪作为对照（XD组）.研究水牛初乳粉对新生仔猪肠道粘膜及肝脏IGF-I、IGF-IR表达量的影响.结果表明,水牛初乳粉使新生仔猪在最初发育的3d内,肠道粘膜和肝脏中IGF-I基因表达量大幅度增加,IGF-I mRNA/β-actin比值高于XD组且P＜0.01;通过IGF-IR基因表达的研究发现,水牛初乳粉能增加肠粘膜中IGF-IR的表达量,但增幅小于IGF-I表达量;在肝脏中,水牛初乳粉使IGF-IR基因表达量略有降低,但与其它两个试验组相比,降低值最小,PY组次之,SC组降低值最大.水牛初乳能显著促进新生仔猪肠道和肝脏IGF-I基因表达,而对IGF-IR基因表达的影响表现为肠粘膜中表达量增加,脏脏中表达量降低.
|
| 关 键 词： | 水牛初乳粉 新生仔猪 IGF-I IGF-IR |
Effects of Buffalo Colostrum Powder on the IGF-I and IGF-IR Gene Expression of Intestinal Mucosa and Liver of Newborn Piglets |
| |
| Chen Ruifang,Geng Dan,Guo Aomin,Zhang HaiyanI,Wang Shichang.Effects of Buffalo Colostrum Powder on the IGF-I and IGF-IR Gene Expression of Intestinal Mucosa and Liver of Newborn Piglets[J].Journal of Shanxi Agricultural University,2013(6):526-530,552. |
| |
| Authors: | Chen Ruifang Geng Dan Guo Aomin Zhang HaiyanI Wang Shichang |
| |
| Institution: | 2 ( 1. J inzhong Vocational and Technical College, Department of Biotechnology ,Wuci Shanxi 030600, China ; 2. College of Animal Science and Technology ,Guangxi University, Nanning Guangxi 530004 , China) |
| |
| Abstract: | Buffalo colostrum is rich in immune globulin, growth factors and other active substances, which have good nutritional function in newborn mammals. The 0-day old newborn piglets were chosen as test object, and were fed with buffalo colostrum powder（SCR）, or mature buffalo milk powder（SC）, or glucose saline（PY）. The effect of buffalo co- lostrums powder on the gene expressions of IGF-I, IGF-IR in intestinal mucosa and liver in newborn piglets were in- ves：tigated. Results showed that the IGF-I gene expression was greatly up-regulated by Buffalo colostrum powder in newborn piglets at the age of 3ds. The relative value of IGF-I mRNA/β-actin was significantly higher than that of the control group（P〈0.01）. The IGF-IR gene expression in intestinal mucosa was found to be upregulated by buffalo co- lostrum powder, but the increase range was less than that of the IGF-I gene. In the liver, the IGF-IR gene expression was slightly downregulated by buffalo colostrum powder which was less than the PY group and the SC group. |
| |
| Keywords: | Buffalo colostrum powder Newborn piglets IGF-I IGF-IR |
| 本文献已被 维普 等数据库收录！ |
|
