| 盐酸克伦特罗对小鼠心肌SOD和GSH-PX活性以及MDA含量的影响 |
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| 引用本文： | 邹本革,刘焕奇,邹明.盐酸克伦特罗对小鼠心肌SOD和GSH-PX活性以及MDA含量的影响[J].安徽农业科学,2009,37(7):2997-2997. |
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| 作者姓名： | 邹本革 刘焕奇 邹明 |
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| 作者单位： | 青岛农业大学动物科技学院,山东青岛,266109;青岛农业大学动物科技学院,山东青岛,266109;青岛农业大学动物科技学院,山东青岛,266109 |
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| 摘 要： | 目的]研究盐酸克伦特罗对小鼠心肌SOD和GSH-PX活性以及MDA含量影响。方法]选用健康雄性小鼠为试验动物,采用腹腔注射法给药,注射不同浓度的盐酸克伦特罗,1次/d,连续给药30 d,末次给药后禁食12 h,脊椎脱臼法处死小鼠,迅速取出心脏,匀浆后测定超氧物歧化酶（SOD）、谷胱苷肽过氧化物酶（GSH-PX）活性以及丙二醛（MDA）的含量。结果]盐酸克伦特罗可使小鼠心肌中SOD和GSH-PX活性显著降低,MDA含量显著升高。结论]大剂量盐酸克伦特罗可降低心肌抗氧化能力。
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| 关 键 词： | 克伦特罗 心肌 抗氧化能力 |
Effects of Clenbuterol on the Activities of SOD,GSH-PX and the Content of MDA of Myocardium in Mice |
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| ZOU Ben-ge et al.Effects of Clenbuterol on the Activities of SOD,GSH-PX and the Content of MDA of Myocardium in Mice[J].Journal of Anhui Agricultural Sciences,2009,37(7):2997-2997. |
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| Authors: | ZOU Ben-ge |
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| Institution: | ZOU Ben-ge et al(College of Animal Science , Technology,Qingdao Agricultural University,Qingdao,Sh,ong 266109) |
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| Abstract: | Objective] The research aimed to study the effects of clenbuterol on the activities of SOD,GSH-PX and the content of MDA of myocardium in mice.Method] The health male mice were chosen as test animals and administrated with different concentration of clenbuterol by intraperitoneal injection for 30 days continuously.Then the feed was stopped for 12 h and mice was killed by using spinal dislocation method.And the heart was isolated and homogenated.Then the levels of SOD,MDA and GSH-PX were detected.Result] ... |
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| Keywords: | Clenbuterol Myocardium Antioxidant capacity |
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