Antibacterial activity and cytotoxicity of extractives from Uvaria hamiltonii stem bark |
| |
| Authors: | Asha K N Chowdhury R Hasan C M Rashid M A |
| |
| Institution: | Faculty of Pharmacy, Department of Pharmaceutical Science, University of Dhaka, Dhaka 1000, Bangladesh. |
| |
| Abstract: | The extracts as well as piperolactum C, goniopedaline, 6beta-hydroxystigmasta-4,22-dien-3-one and a mixture of cis- and trans-4-hydroxymelleins obtained from Uvaria hamiltonii stem bark exhibited mild to moderate in vitro antibacterial activity. The results obtained were compared with a standard antibiotic, kanamycin. In a brine shrimp lethality bioassay the pet-ether, dichloromethane, methanol extracts and a major alkaloid, piperolactum C were found to exhibit mild to moderate cytotoxicity. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ |
|
