| 仔猪人工感染猪囊尾蚴后外周血中淋巴细胞亚群的动态变化研究 |
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| 引用本文： | 徐鹏,杨桂连,刘孝刚,蔡亚南,姜晶,赵权.仔猪人工感染猪囊尾蚴后外周血中淋巴细胞亚群的动态变化研究[J].吉林农业大学学报,2007,29(4):440-442. |
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| 作者姓名： | 徐鹏 杨桂连 刘孝刚 蔡亚南 姜晶 赵权 |
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| 作者单位： | 吉林农业大学动物科技学院,长春,130118;辽宁医学院畜牧兽医学院,锦州,121001;吉林农业大学动物科技学院,长春,130118;辽宁医学院畜牧兽医学院,锦州,121001 |
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| 基金项目： | 国家自然科学基金(30571396) |
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| 摘 要： | 试验研究了仔猪人工感染猪囊尾蚴后外周血中CD_3~ 、CD_4~ 、CD_8~ T淋巴细胞的变化规律。将10头仔猪随机分为2组,即攻虫组和对照组,每组5头,用流式细胞仪检测攻虫后10,20,30,40,70 d试验猪外周血中T淋巴细胞亚群的变化情况。结果显示整个检测过程中CD_3~ T细胞比例一直处于较低水平。在感染初期CD_4~ T细胞和CD_8~ T细胞比例明显降低,且CD_4~ T细胞比例明显高于CD_8~ T细胞;感染中期CD_8~ T细胞数量有所增加,但仍以CD_4~ T细胞比例占优势;感染后期CD_4~ T细胞和CD_8~ T细胞数量都有所恢复。
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| 关 键 词： | 猪囊尾蚴 细胞免疫 流式细胞术 |
| 文章编号： | 1000-5684（2007）04-0440-03 |
| 修稿时间： | 2006-06-192006-11-10 |
Study on Dynamic Changes of T Lymphocytes Subsets in Peripheral Blood of Piglets with Cysticercosis cellulosae by Artificial Infection |
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| XU Peng,YANG Gui-lian,LIU Xiao-gang,CAI Ya-nan,JIANG Jing,ZHAO Quan.Study on Dynamic Changes of T Lymphocytes Subsets in Peripheral Blood of Piglets with Cysticercosis cellulosae by Artificial Infection[J].Journal of Jilin Agricultural University,2007,29(4):440-442. |
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| Authors: | XU Peng YANG Gui-lian LIU Xiao-gang CAI Ya-nan JIANG Jing ZHAO Quan |
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| Institution: | 1. College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China; 2. College of Animal Husbandry and Veterinary Medicine; Liaoning Medical University, Jinzhou 121001, China |
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| Abstract: | To explore the dynamic changes of cytokines including CD_3~ ,CD_4~ ,CD_8~ in T.lymphocytes of peripheral blood of piglets with Cysticercosis cellulosae by artificial infection.Methods:All piglets were grouped 2 at random,infected group and contract group,the percentages of CD_3~ ,CD_4~ ,CD_8~ in T.lymphocytes of peripheral blood were analyzed using flow cytometry after 10,20,30,40,70 days' in- fection.The percentage of CD_3~ T cells was low in level in the whole detection process.In the early days of infection,the percentages of CD_4~ and CD_8~ were stepped down,furthermore CD_4~ T cells were higher than CD_8~ T cells;In the intermediate stage of infection,CD_8~ T cells increased,but CD_4~ T cells were still predominant.In the later stage of infection,the percentage of CD_4~ and CD_8~ T were cells all re- vived. |
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| Keywords: | Cysticercosus cellulosae cellular immunity flow cytometry |
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