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镉对鸡肝脏抗氧化系统功能以及中药四君子汤拮抗效应的影响研究
引用本文:陈强,肖银霞,王立成,姜莉莉.镉对鸡肝脏抗氧化系统功能以及中药四君子汤拮抗效应的影响研究[J].中国农学通报,2012,28(23):66-68.
作者姓名:陈强  肖银霞  王立成  姜莉莉
作者单位:辽宁医学院,辽宁锦州,121001
基金项目:辽宁医学院青年科技启动基金项目“中草药拮抗鸡亚慢性镉中毒肝脏损伤效应的研究”(Y2010Z023)
摘    要:为探讨中药四君子汤对镉中毒鸡肝脏GSH-Px、SOD活性抑制的拮抗作用。选用60只100日龄海兰公鸡,随机平均分为3组,对照组常规饲养,加镉组常规饲养的同时,添加CdCl2 150 mg/kg,中药四君子汤加镉组常规饲养的同时,添加CdCl2 150 mg/kg,添加1%中药四君子汤。分笼常规饲养,试验期为60天,这样就建立了亚慢性镉中毒及中药四君子汤拮抗模型。试验结果显示:肝脏谷胱甘肽过氧化物酶(GSH-Px)活性为对照组、中药四君子汤加镉组至加镉组依次降低;肝脏超氧化物歧化酶(SOD)活性为对照组、中药四君子汤加镉组至加镉组依次降低;肝脏丙二醛(MDA)含量为对照组、中药四君子汤加镉组至加镉组依次升高。表明日粮中添加中药四君子汤后可有效地提高机体的抗氧化能力。

关 键 词:品种筛选  品种筛选  
收稿时间:2012/1/13 0:00:00
修稿时间:3/8/2012 12:00:00 AM

Research on Effect of Cadmium on Antioxidation System of Chicken Liver and Antagonistic Effect of the Traditional Chinese Medicine Sijunzi
Chen Qiang , Xiao Yinxia , Wang Licheng , Jiang Lili.Research on Effect of Cadmium on Antioxidation System of Chicken Liver and Antagonistic Effect of the Traditional Chinese Medicine Sijunzi[J].Chinese Agricultural Science Bulletin,2012,28(23):66-68.
Authors:Chen Qiang  Xiao Yinxia  Wang Licheng  Jiang Lili
Institution:(Liaoning Medical University, Jinzhou Liaoning 121001)
Abstract:In order to explore the traditional Chinese medicine Sijunzi' s antagonism to the activity of GSH-Px and SOD in cadmium poisoning chicken liver, 60 100-day-age Hayland roosters were selected to be divided into 3 random average groups. Control group1 was fed with the usual method. Control group 2 was fed with the usual method and added with cadmium the concentration of 150 mg/kg. Control group 3 was fed with the usual method, cadmium of 150 mg/kg and Sijunzi. All 3 groups were fed with normal diet in each cage. liver GSH-Px activity was set as control group. The group of Sijunzi with cadmium to the group of cadmium were declined in turn; liver SOD activity was set up as control group, the group of Sijunzi with cadmium to the group of cadmium were declined in turn; set liver MDA content as control group, the group of Sijunzi with cadmium to the group of cadmium were increased in turn. The experiment indicated that daily diet added with traditional Chinese medicine Sijunzi could effectively improved the body' s oxidation resistance.
Keywords:cadmium  traditional Chinese medicine Sijunzi  chicken  antagonism  antioxidant defense system
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