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| 长效恩诺沙星注射液在健康猪体内的药动学 | |
| 引用本文： | 周云波,吴海燕,鞠晓峰,郭艳清,完善春,陈志宝.长效恩诺沙星注射液在健康猪体内的药动学[J].黑龙江八一农垦大学学报,2005,17(3):70-72. |
| 作者姓名： | 周云波 吴海燕 鞠晓峰 郭艳清 完善春 陈志宝 |
| 作者单位： | 1. 黑龙江省泰来县泰来镇畜牧站,泰来镇,162400 2. 黑龙江八一农垦大学 3. 鸡东县畜牧局 4. 鸡西市畜牧局 |
| 摘 要： | 为了解长效恩诺沙星在健康猪体内的药动力学,进行了本研究。应用HPLC法测定血浆药物浓度,所得数据用MCPKP药代力学软件处理。实验结果表明,长效恩诺沙星注射剂药物半衰期明显延长,差异显著性P<0.01,生物利用度有所提高。 |
| 关 键 词： | 恩诺沙星 药动学 HPLC 猪 |
| 文章编号： | 1002-2090(2005)03-0070-03 |
Pharmacokinetics of Enroofloxacin in Healthy Pig |
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| ZHOU Yun-bo,WU Hai-yan,JU Xiao-feng et al..Pharmacokinetics of Enroofloxacin in Healthy Pig[J].Journal of Heilongjiang August First Land Reclamation University,2005,17(3):70-72. | |
| Authors: | ZHOU Yun-bo WU Hai-yan JU Xiao-feng |
| Abstract: | To make sure the pharmacokinetic characterisrics of enrofloxacin inuhealthy pig were studied. The concentrations of enrofloxacin and its metabolite were determined by a high performance liquid chromatography (HPLC).The c-t data of enrofloxacin in plasm were analysed with MCPKP program. The results showed that the elimination half life could prolong significantly and P<0.01. |
| Keywords: | enrofloxacin pharm acok inetics HPLC swine |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |