Evaluation of oral therapy on Mansonial Schistosomiasis using single dose of Balanites aegyptiaca fruits and praziquantel |
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| Authors: | Koko W S Abdalla H S Galal M Khalid H S |
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| Institution: | Medicinal and Aromatic Plants Research Institute, National Centre for Research, P.O. Box 2404, Khartoum, Sudan. wasyko2002@yahoo.com |
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| Abstract: | The efficacy of Balanites aegyptiaca fruit mesocarp was compared with praziquantel in mice infected with Sudanese strain of Schistosoma mansoni. Infected mice were given a single dose of 200 mg/kg body weight of B. aegyptiaca fruit mesocarp and 200 mg/kg b.w. of praziquantel after 6 weeks from the onset of the infection. A significant reduction was observed in EPG (egg count per gram of faeces), eggs burden in tissues and recovery of adult worms (P<0.05) for both the plant and the drug-treated animals. |
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