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Actin-myosin interaction: inhibition of the myosin adenosine triphosphatase by actin |
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| Authors: | S Barron E Eisenberg C Moos |
| Abstract: | In the absence of magnesium ion, the addition of actin to myosin in a 1 :4 ratio has a strong inhibitory effect on the adenosine triphosphatase activity, in contrast to the well-known activating effect of actin in the presence of magnesium ion. This finding suggests that both effects result from a conformational change in the active site of the myosin adenosine triphosphatase. |
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