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复方芩连汤对几种禽病病毒体外增殖的抑制作用
引用本文:王学斌,魏战勇,崔保安,胡梅,徐端红.复方芩连汤对几种禽病病毒体外增殖的抑制作用[J].河南农业科学,2007(8):99-104.
作者姓名:王学斌  魏战勇  崔保安  胡梅  徐端红
作者单位:河南农业大学,牧医工程学院,河南,郑州,450002
基金项目:河南省农业科技成果转化项目
摘    要:以黄连、黄芩、板蓝根、黄芪等为主要成分的复方芩连汤作为抗病毒药,利用细胞病变(CPE)抑制试验测定中药复方在长成单层的鸡胚成纤维细胞(CEFC)上对鸡新城疫病毒(NDV)、鸡传染性支气管炎病毒(IBV)、鸡传染性法氏囊病病毒(IBDV)等几种禽病病毒的抑制作用。结果表明:中药复方对NDV具有较好的抑制作用,其最小直接杀灭浓度为7.81μg/mL,最小阻断浓度为3.9μg/mL,最小治疗浓度为15.62μg/mL;中药复方在体外对IBV的T株和M41株也具有显著定的抑制作用,而对IBDV的抑制作用则不明显。

关 键 词:中药复方  新城疫病毒  鸡传染性支气管炎病毒  鸡传染性法氏囊病病毒
文章编号:1004-3268(2007)08-0099-06
修稿时间:2007-03-12

The Anti-avian Virus Effect of Traditional Chinese Herbal Medicine Compound in Vitro
WANG Xue-bin,WEI Zhan-yong,CUI Bao-an,HU Mei,XU Duan-hong.The Anti-avian Virus Effect of Traditional Chinese Herbal Medicine Compound in Vitro[J].Journal of Henan Agricultural Sciences,2007(8):99-104.
Authors:WANG Xue-bin  WEI Zhan-yong  CUI Bao-an  HU Mei  XU Duan-hong
Institution:Engineering College of Animal and Vetrinary Science, Henan Agricultural University, Zhengzhou 450002, China
Abstract:The traditional Chinese herbal medicine is composed mainly of the following Chinese medicine:coptis Chinesis Franch,Scutellaria baicalensis Georgi,Isatis indigotica Fort,Astragalus membranceus,etc,and its antivirus effects to several poutry virus(NDV,IBV,IBDV,etc.) were tested on the chick embryo fibroblast cell(CEFC) in vitro.The result showed that the compound could inhibit NDV and IBV infection significantly,had little effect on IBDV.So it may be used in treating,and even preventing ND,IB and IBD in Avian.
Keywords:Traditional Chinese herbal medicine compound  Newcastl Bronchitis virus  Infectious bursal disease virus ect on IBDV  So it may be e disease virus  Infectious
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