| 诺氟沙星在草鱼体内的残留规律研究 |
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| 引用本文： | 郭海燕,张其中.诺氟沙星在草鱼体内的残留规律研究[J].水产养殖,2009,30(10):24-26. |
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| 作者姓名： | 郭海燕 张其中 |
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| 作者单位： | 1. 西南大学生命科学学院,重庆,400715;重庆市水产科学研究所,重庆,400020
2. 西南大学生命科学学院,重庆,400715;暨南大学水生生物研究所,广东,广州,510632 |
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| 摘 要： | 研究了多剂量混饲口灌给药方式下,诺氟沙星在草鱼体内的残留消除情况。结果显示：以每千克鱼体重10 mg连续5d混饲给药后,停药后第12天在草鱼肌肉中未检测到药物,此时血清、肝脏和肾脏中的药物浓度分别降为（0.0287±0.0015）μg/mL、（0.0181±0.0042）μg/g和（0.0369±0.0037）μg/g,均低于0.05μg/mL或0.05μg/g。因此初步建议在（19±1）℃水温条件下,以每千克鱼体重10 mg连续5 d混饲给草鱼诺氟沙星,休药期至少为最后一次给药后的12 d。
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| 关 键 词： | 草鱼 诺氟沙星 体内残留 |
Residues Regulation of Norfloxacin in Ctenopharyngodon idellus |
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| Guo Haiyan,Zhang Qizhong.Residues Regulation of Norfloxacin in Ctenopharyngodon idellus[J].Journal of Aquaculture,2009,30(10):24-26. |
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| Authors: | Guo Haiyan Zhang Qizhong |
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| Institution: | Guo Haiyan, Zhang Qizhong( 1. Southwest University, Chongqing 400715, China; 2.Chongqing fishery Sciences Research Institute, Chongqing 400020, China; 3.Hydrobiology Institute of Jinan University, Guangzhou 510632, China) |
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| Abstract: | The study investigated residues of norfloxacin（NFX）in Ctenopharyngodon idellus L.The results showed that after continuously administrated with feed at the dosage of 10 mg/kg NFX per day for 5 days,no drugs was detected in muscle and the concentration in serum,liver and kidney were（0.0287±0.0015）μg/mL,（0.0181±0.0042）μg/g and（0.0369±0.0037）μg/g respectively,all below 0.05μg/mL or 0.05 μg/g.Therefore,we suggest a withdrawal period should last at least for 12 days in C.idellus at the water temperature（19±1）℃ after they had been administered with feed at a dosage of 10 mg/kg NFX per day for 5 days. |
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| Keywords: | Ctenopharyngodon idellus L Norfloxacin residues |
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