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Baseline susceptibility of a wild strain of Phlebotomus papatasi (Diptera: Psychodidae) to DDT and pyrethroids in an endemic focus of zoonotic cutaneous leishmaniasis in Iran
Authors:Saeidi Zahra  Vatandoost Hassan  Akhavan Amir Ahmad  Yaghoobi-Ershadi Mohamad Reza  Rassi Yavar  Sheikh Zahra  Arandian Mohamad Hossein  Jafari Reza  Sanei Dehkordi Ali Reza
Institution:Department of Medical Entomology and Vetcor Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:BACKGROUND: Phelebotumus papatsi is considered to be the main vector of zoonotic cutaneous leishmaniasis as well as sand fly fever in Iran. There are several measures for vector control, with emphasis on insecticides. The objective of this study was to determine the baseline susceptibility of this vector to the commonly used insecticides in an endemic focus of the disease in central Iran. P. papatasi collected from the field were used for susceptibility status. Its baseline susceptibility to DDT and pyrethroids was assessed on about 6866 specimens collected from Badrood rural district, Esfahan Province, Iran, during the summer of 2010. The LT50 and LT90 values were measured according to the World Health Organisation (WHO) test using probit analysis and regression lines. RESULTS: Results of tests against female P. papatasi revealed LT50 values to DDT 4%, permethrin 0.75%, deltamethrin 0.1%, cyfluthrin 0.15% and lambdacyhalothrin 0.05% of 1104.97, 182.35, 26.79, 15.42 and 1.48 s respectively. The figures for male P. papatasi were 973.51, 59.5, 4.4, 2.65 and 1.5. CONCLUSION: The results of this study provide a guideline for implementation of different vector control measures. Furthermore, guidelines are needed for monitoring and evaluation of insecticide susceptibility tests against sand flies. Copyright © 2012 Society of Chemical Industry
Keywords:Phlebotomus papatasi  insecticides  susceptibility  Iran
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