New bibenzyl glycosides from leaves of Camellia oleifera Abel. with cytotoxic activities |
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| Authors: | Yuelong ChenLing Tang Baomin Feng Liying ShiHuiguo Wang Yongqi Wang |
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| Institution: | a College of Bioengineering, Dalian University, Dalian 116622, Chinab Liaoning Key Lab of Bioorganic Chemistry, Dalian University, Dalian 116622, China |
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| Abstract: | Studies on the chemical constituents of leaves of Camellia oleifera Abel. led to the isolation of 3 new bibenzyl glycosides. Their structures have been elucidated as 1-(3′,5′-dihydroxy)phenyl-2-(4″-O-β-D-glucopyranosyl)phenylethane (1), 1-(3′,5′-dimethoxy)phenyl-2-(4″-O-β-D-glucopyranosyl)phenylethane (2) and 1-(3′,5′-dimethoxy)phenyl-2-4″-O-β-D-glucopyranosyl(6→1)-O-α-L-rhamnopyranosyl]phenylethane (3) through spectral studies including HR-ESI-MS, 1H NMR, 13C NMR and 2D NMR experiments. All the above 3 bibenzyl glycosides showed cytotoxic activities to Hela and hep2 cell lines. |
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| Keywords: | Camellia oleifera Abel Theaceae Bibenzyl glycosides Cytotoxic activities |
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