| 蛹虫草对小鼠体液免疫功能和NK细胞活性的影响 |
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| 作者姓名： | 赵宏宇 崔林虎 张伟云 |
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| 作者单位： | 吉林省中医药科学院;延边林业科学研究院;长春工业大学 |
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| 基金项目： | 中央财政林业科技推广示范资金项目(JLT[2016]7)。 |
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| 摘 要： | 目的]探讨蛹虫草对小鼠体液免疫功能和NK细胞活性的影响。方法]以83.3、166.7、333.3 mg/kg·BW剂量的蛹虫草给予小鼠灌胃30 d。结果]灌胃30 d后同对照组比较,各剂量组对小鼠体重、脾/体重、胸腺/体重比值无影响(P>0.05),中、高剂量组能显著升高小鼠血清半数溶血值(P<0.05),中、高剂量组能显著增强抗体生成细胞能力(P<0.05),各剂量组均能增强小鼠NK细胞活性(P<0.05)。结论]蛹虫草具有增强体液免疫功能和NK细胞活性的作用。
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| 关 键 词： | 蛹虫草 体液免疫功能 NK细胞活性 |
Effect of Cordyceps militaris on Humoral Immunity and NK Cell Activity of Mice |
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| Institution: | (Jilin Provincial Academy of Chinese Medicine,Changchun,Jilin 130021) |
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| Abstract: | Objective]To study effect of Cordyceps militaris on humoral immunity function and NK cell activity of mice.Method]The male mice were given a dose of 83.3,166.7,333.3 mg/kg·BW for 30 days testing.Result]Cordyceps militaris had no significant effect on body weight increase,ratio of spleen weight to body weight,ratio of thymus weight to body weight(P>0.05).Middle and high dose groups had significant effects on HC50(P<0.05)and had significant effect on quantity of antibody forming cells(P<0.05).All groups could significantly enhance the NK cell activity of mice.Conclusion]Cordyceps militaris could strengthen humoral immunity function and NK cell activity. |
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| Keywords: | Cordyceps militaris Humoral immunity NK cell activity |
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