Thromboelastography: a tool for measuring hypercoagulability, hypocoagulability, and fibrinolysis |
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| Authors: | Suzanne M Donahue VMD DACVECC and Cynthia M Otto DVM PhD DAVECC |
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| Institution: | From the Section of Critical Care, Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA |
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| Abstract: | Objective: To describe the technique of thromboelastography (TEG) and review the applications of this coagulation test in humans and small animals. Data sources: Data sources included scientific reviews and original research publications. Human data synthesis: TEG in humans has been used for documentation of hypercoagulable and hypocoagulable states and has been shown to be beneficial in patient management. Veterinary data synthesis: Clinical evaluation of TEG in veterinary medicine is limited; however, recent reports have documented evidence of hypercoagulability in dogs with parvovirus and protein‐losing nephropathy. Additionally, many of the research models may be relevant to veterinary patients. Conclusions: TEG provides information about coagulation that is not available through routine coagulation tests. The application of TEG monitoring to veterinary patients shows promise; however, prospective clinical studies are needed. |
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| Keywords: | coagulation disseminated in travascular coagulation heparin monitoring thrombosis |
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