Large granular lymphocytic leukemia in a mixed breed dog |
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Authors: | Lau K W Kruth S A Thorn C E Vernau W Moore P |
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Institution: | Department of Clinical Studies, Ontario Veterinary College, University of Guelph. |
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Abstract: | A mixed breed dog was diagnosed with large granular lymphocytic leukemia. Immunophenotypic analysis indicated the lymphocytes were CD3+, CD8+ T cells expressing the alpha beta T cell receptor and a leukointegrin, alpha d. Chemotherapy and splenectomy resulted in an initial reduction in the lymphocyte count. |
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