East coast fever: 4. Further studies on the protection of cattle immunized with a combination of theilerial strains |
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| Authors: | TT Dolan DE Radley CGD Brown MP Cunningham SP Morzaria AS Young |
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| Institution: | Veterinary Research Department, Kenya Agricultural Research Institute, Muguga, P.O. Box 32, Kikuyu, Kenya |
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| Abstract: | Four experiments were carried out in which cattle immunized with three cryopreserved stabilates, Theileria parva (Muguga), T. parva (Kiambu 5) and T. lawrencei (Serengeti transformed) and simultaneously treated with a single dose of long acting tetracycline were challenged with field isolates of T. parva. Three of the challenge isolates were from Tanzania and one from Kenya. The immunized cattle showed either mild or inapparent diease reations while susceptible control cattle suffered severe disease and 72% died. These experiments further demonstrated the efficacy of the immunization method against T. parva isolates from a wide distribution within East Africa. The value of such laboratory screening of field isolates prior to field exposures is discussed. |
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