| 动物病毒microRNA的研究进展 |
| |
| 引用本文： | 薛白,王树芬,鲍登克,邓瑞广,李学伍.动物病毒microRNA的研究进展[J].河南农业科学,2012,41(6):15-18. |
| |
| 作者姓名： | 薛白 王树芬 鲍登克 邓瑞广 李学伍 |
| |
| 作者单位： | 1. 河南科技大学动物科技学院,河南洛阳471003;河南省农业科学院农业部动物免疫学重点开放实验室/河南省动物免疫学重点实验室,河南郑州450002
2. 河南省农业科学院农业部动物免疫学重点开放实验室/河南省动物免疫学重点实验室,河南郑州,450002 |
| |
| 基金项目： | 国家自然科学基金项目(3117234) |
| |
| 摘 要： | MicroRNAs(miRNAs)是一种含有约22～25个核苷酸的非编码单链RNA分子,广泛存在于人类及其他各种生物中。它通过与靶mRNA特异性的碱基互补配对,引起靶mRNA降解或者抑制其翻译,从而调节基因的转录后表达水平。病毒microRNA是新发现的一类miRNA,综述了近年来病毒microRNA的产生、作用机制、生物学功能及其在动物上的研究进展。
|
| 关 键 词： | 病毒 microRNA 基因调控 动物疾病 |
Progress on the Research of Viral MicroRNAs Involved in Animal Disease |
| |
| XUE Bai
,
WANG Shu-fen
,
BAO Deng-ke
,
DENG Rui-guang
,
LI Xue-wu.Progress on the Research of Viral MicroRNAs Involved in Animal Disease[J].Journal of Henan Agricultural Sciences,2012,41(6):15-18. |
| |
| Authors: | XUE Bai WANG Shu-fen BAO Deng-ke DENG Rui-guang LI Xue-wu |
| |
| Institution: | 1.College of Animal Science and Technology,Henan University of Science and Technology,Luoyang 471003,China; 2.Key Laboratory of Animal Immunology of the Ministry of Agriculture/Henan Provincial Key Laboratory of Animal Immunology,Henan Academy of Agricultural Sciences,Zhengzhou 450002,China) |
| |
| Abstract: | MicroRNAs(miRNAs)are a class of non-coding small RNA in length of 22-25 nt and distribute extensively in human and other organism genomes.They regulate gene expression through sequence specific interactions with target mRNAs resulting in translational repression or mRNA degradation.Viral microRNAs are a class of newly discovered miRNA.This paper introduces the progress on the researches of the generation,functions and mechanisms of viral micro-RNAs and its function involved in animal diseas. |
| |
| Keywords: | virus microRNA gene regulation animal disease |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
