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| SRY基因调控网络的研究进展 | |
| 引用本文： | 赵金红,赵金艳,黄勇富,林秀坤.SRY基因调控网络的研究进展[J].四川畜牧兽医,2010,37(8):29-30,33. |
| 作者姓名： | 赵金红 赵金艳 黄勇富 林秀坤 |
| 作者单位： | 1. 重庆市畜牧科学院,重庆,荣昌,402460 2. 郑州牧业高等专科学校,河南,郑州,450008 3. 北京畜牧兽医研究所,北京,100094 |
| 摘 要： | 性别决定过程可能是以SRY基因为主导，由一系列上游或下游基因参入和协调的级联反应过程。研究发现，DMRT1、SOX9、SF1、WT1、LIM1、LHX9和DAX1等基因对动物性别的决定和性器官的分化起着重要作用。本文就SRY及性别相关基因调控网络的研究进展作一综述。 |
| 关 键 词： | SRY 调控网络 |
Research on the progress of SRY regulation network |
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| Institution: | ZHAO Jin-hong, ZHAO Jin-yan, HUANG Yong-fu, et al. ( I.Chongqing Academy of Animal Science, Chongqing Rongchang 402460, China ; 2.Zhengzhou College of Animal Husbanry Engineering, Henan Zhengzhou 450008, China; 3.Institute of Animal Science, Chinese Academy of Agricultural Science, Beijing 100094, China ) |
| Abstract: | Since Sry was discovered numberous genes have been suggested in the literature comprising the chain of gene expression for male differentiation. There are many evidences to show that SRY is at the top of the cascade of genetic activity leading to male development in mammals. The functions of some genes,such as WT1, SF1, SP1, SOX9, DMRT1 and DMRT2, have already been defined in male gonadal morphogenesis. This paper presented a review of the genes involved in the formation of the male gonad in mammals. |
| Keywords: | SRY |
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