| 猪胰岛素样生长因子I基因表达与调控的研究进展 |
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| 引用本文： | 肖书奇,李爽,张嘉保,任文陟,刘保国,赵志辉,赵中利,张树敏.猪胰岛素样生长因子I基因表达与调控的研究进展[J].家畜生态,2007(4). |
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| 作者姓名： | 肖书奇 李爽 张嘉保 任文陟 刘保国 赵志辉 赵中利 张树敏 |
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| 作者单位： | 吉林大学农学部实验动物中心 吉林长春130062(肖书奇，李爽，张嘉保，任文陟，赵志辉，赵中利)，河南科技学院动物科学学院 河南新乡453003(刘保国)，吉林省农业科学院畜牧分院 吉林公主岭136100(张树敏) |
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| 基金项目： | 国家振兴东北老工业基地科技攻关项目(2004BA907A22)资助 |
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| 摘 要： | 胰岛素样生长因子-I(I nsulin-like growth factor-I,I GF-I)是机体生长、发育和代谢的一个重要调控因子,同时也是生长激素(growth hormone,GH)启动生长活性的主要介导者。血液中的I GF-I主要来源于肝脏,以内分泌的形式作用于其他组织;许多肝外组织也能合成I GF-I,其主要以自分泌或旁分泌的形式发挥作用。多种因素调控其表达。本文就猪I GF-I的表达与调控方面的最新研究进展进行一综述。
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| 关 键 词： | 猪 胰岛素样生长因-子I 表达 调控 |
Expression and Regulation of the Pig Insulin-like Growth Factor-IGene |
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| XIAO Shu-qi,LI Shuang,ZHANG Jia-bao,REN Wen-zhi,LIU Baoguo,ZHAO Zhi-hui,ZHAO Zhong-Li,ZHANG Shu-min.Expression and Regulation of the Pig Insulin-like Growth Factor-IGene[J].Ecology of Domestic Animal,2007(4). |
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| Authors: | XIAO Shu-qi LI Shuang ZHANG Jia-bao REN Wen-zhi LIU Baoguo ZHAO Zhi-hui ZHAO Zhong-Li ZHANG Shu-min |
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| Institution: | XIAO Shu-qi1,LI Shuang1,ZHANG Jia-bao1,REN Wen-zhi1,LIU Baoguo2,ZHAO Zhi-hui1,ZHAO Zhong-Li1,ZHANG Shu-min3 |
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| Abstract: | Insulin-like growth factor-I(IGF-I) is an important regulator of growth,development,metatabolism,and is the primary mediator of the growth-promoting activity of growth hormone(GH) in mammals.The primary source of IGF-I is the liver,from which IGF-I is released into the blood and acts in an endocrine mode on other tissues.IGF-I is also synthesized in many extrhepatic tissues,where it functions in an autocrine or paracrine manner.IGF-I gene expression is controlled by many factors.This article reviewed the latest research progress of expression and regulation of the pig IGF-I gene. |
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| Keywords: | pig insulin-like growth factor-I expression regulation |
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