ADCC and complement-dependent lysis as immune mechanisms against EHV-1 infection in the horse |
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| Authors: | A Stokes R C Wardley |
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| Institution: | Animal Virus Research Institute, Pirbright, Woking, Surrey. |
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| Abstract: | Immunity to equine herpesvirus type 1 (EHV-1) was evaluated using sera collected from yearling horses involved in a trial of a commercial vaccine. Measurement of the ability of these sera to mediate antibody-dependent cellular cytotoxicity and complement-dependent lysis revealed that these mechanisms, although potentially important in recovery from EHV-1 infection, do not play a role in protection following vaccination. |
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