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Oxygenated Ylangene-Derived Sesquiterpenoids from the Soft Coral Lemnalia philippinensis
Authors:Yun-Jie Xio  Jui-Hsin Su  Bo-Wei Chen  Yen-Ju Tseng  Yang-Chang Wu  Jyh-Horng Sheu
Abstract:Chemical examination of a Taiwanese soft coral Lemnalia philippinensis led to the isolation of three oxygenated ylangene-derived sesquiterpenoids 1–3, including two new metabolites, philippinlins A and B (1 and 2). The structures of these compounds were elucidated on the basis of detailed spectroscopic data. Compound 1 was shown to exhibit cytotoxicity against HepG2, MDA-MB231 and A549 cancer cell lines.
Keywords:Lemnalia philippinensis  ylangene  philippinlins A and B  cytotoxicity
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