| 免疫乳及血液中抗痢疾志贺氏菌抗体消长规律的研究 |
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| 引用本文： | 李留安,王月影,王艳玲,杨国宇,李宏基,许兰菊.免疫乳及血液中抗痢疾志贺氏菌抗体消长规律的研究[J].安徽农业科学,2010,38(4):1855-1856. |
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| 作者姓名： | 李留安 王月影 王艳玲 杨国宇 李宏基 许兰菊 |
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| 作者单位： | 1. 河南农业大学牧医工程学院,河南郑州,450002;天津农学院动物科学系,天津,300384
2. 河南农业大学牧医工程学院,河南郑州,450002 |
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| 基金项目： | 河南省科技攻关项目(072102140002);;河南省杰出人才创新基金项目(0121000300);;天津农学院科学研究发展基金计划博士启动基金项目(2008D010) |
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| 摘 要： | 目的]为抗痢疾志贺氏菌抗体免疫乳的研制和开发提供理论依据。方法]以痢疾志贺氏菌为免疫原对妊娠后期的奶牛进行强化免疫,定期检测奶牛血和乳中的特异性抗体水平,以研究抗体消长规律。结果]首次免疫后60d内,试验和对照血中的抗体效价均急剧上升且试验组的上升幅度明显大于对照组。分娩当天,试验血和乳中的抗体效价分别为12.2和10.4,对照血和乳中的分别为6.4和4.6;分娩后3d内,试验乳中的抗体效价比对照乳高6个滴度左右。分娩后第7天,试验血和乳中的抗体效价分别为10.8和9.2,对照血和乳中的分别为4.2和2.6。在常乳期间,试验血和乳中的抗体效价均缓慢下降。分娩后大约84d,试验血和乳中的抗体效价分别降至5.6和3.6。结论]该研究为免疫乳的开发和生产奠定了理论基础。
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| 关 键 词： | 免疫乳 痢疾志贺氏菌 抗体消长规律 |
Study on the Dynamic Changes of Antibodies of Shigella dysenteriae in Immune Milk and Blood |
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| LI Liu-an et al.Study on the Dynamic Changes of Antibodies of Shigella dysenteriae in Immune Milk and Blood[J].Journal of Anhui Agricultural Sciences,2010,38(4):1855-1856. |
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| Authors: | LI Liu-an |
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| Institution: | College of Animal Husbandry and Veterinary Engineering;Henan Agricultural University;Zhengzhou;Henan 450002 |
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| Abstract: | Objective]The aim of the study was to supply theoretical foundation for the preparation and development of immune milk with antibodies of Shigella dysenteriae.Method]The cows in late pregnancy were treated by intensive immunization with S.dysenteriae as immunogen and the levels of specific antibodies in their blood and milk were determined periodically to study the dynamic changes of the antibodies.Result]In 60 d since first immunization,both the antibody titers in tested and control blood were increased... |
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| Keywords: | Immune milk Shigella dysenteriae Dynamic changes of antibodies |
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