Antifeedant activity of some pentacyclic triterpene acids and their fatty acid ester analogues |
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| Authors: | Mallavadhani Uppuluri V Mahapatra Anita Raja S Sabitha Manjula C |
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| Institution: | Forest and Marine Products Department, Natural Resources Division, Regional Research Laboratory (CSIR), Bhubaneswar-751 013, Orissa, India. uvmavadani@yahoo.com |
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| Abstract: | The 3-O-fatty acid ester derivatives (C(12)-C(18)) of two pentacyclic triterpenic acids, ursolic acid and oleanolic acid, were synthesized under mild esterification conditions in excellent yields (80-85%) and screened for their antifeedant activity, together with the parent acids, against the agricultural pest tobacco caterpillar larvae (Spodoptera litura F) in a no-choice laboratory study. The Urs-12-ene-28-carboxy-3beta-octadecanoate and olean-12-ene-28-carboxy-3beta-hexadecanoate were found to exhibit exceptionally potent antifeedant activities at 50 microg/cm(2) concentration, even after 48 h. |
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