| 党参多糖口服液抗应激及抗炎作用的研究 |
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| 引用本文： | 侯丽丽,晏永新.党参多糖口服液抗应激及抗炎作用的研究[J].中国兽药杂志,2013,47(11):37-39. |
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| 作者姓名： | 侯丽丽 晏永新 |
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| 作者单位： | 山西省兽药监察所;江西新世纪民星动物保健品有限公司,江西新世纪民星动物保健品有限公司 |
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| 摘 要： | 为研究党参多糖口服液的抗应激与抗炎作用,给小鼠灌服不同剂量（每kg体重灌服9、7、5 g生药）的党参多糖口服液后,通过测定小鼠负重游泳时间、常压耐缺氧时间来评价其应激性作用;观察党参多糖口服液对小鼠耳廓二甲苯致炎的影响,考察其抗炎作用.结果显示,党参多糖口服液能显著（P＜0.01）延长小鼠的游泳时间和常压缺氧条件下的存活时间,对二甲苯所致小鼠耳廓炎症具有不同程度的抑制作用.因此,党参多糖口服液具有抗应激、抗炎作用,该试验可为党参多糖口服液的临床应用提供参考.
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| 关 键 词： | 党参多糖口服液 应激性 抗炎作用 小鼠 |
| 收稿时间： | 2013/8/26 0:00:00 |
| 修稿时间： | 2013/10/11 0:00:00 |
The Anti-stress Ability and Anti-inflammation Effect of Codonopsis pilosula Polysaccharide Oral Liquids |
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| Institution: | Shanxi Institute of Veterinary Drug Control;Jiangxi New Century Minxing Animal Health Products Co,Ltd Jiangxi Nanchang, |
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| Abstract: | After the mouse are feed different dosages of Codonopis pilosula polysaccharide oral liquids （5 g crude drug/kg, 7 g crude drug/kg, 9 g crude drug/kg）, their role of stress is evaluated by the time of loaded swimming and hypoxia tolerance, and their anti - inflammatory effect is investigated by the influence of inflammatory of mouse＇ s ear, induced by xylene. The result is that the Codonopis pilosula polysaccharide oral liquids （P 〈 0. 01 ） can outstanding prolongs the time of swimming of mouse and survival in the conditions of atmospheric pressure and hypoxia, and the inflammation of mouse＇ s ears, induced by xylene, is restrained with different levels. Those prove that the Codonopis pilosula polysaccharide oral liquids have apparent function of anti - stress and anti - inflammatory. This research can provide a reference for the clinical uses of Codonopis pilosula polysacehafide oral liquids. |
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| Keywords: | Codonopsis pilosula polysaccharide oral liquids stress ability anti-inflammatory effects mice |
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