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发酵乳中多糖的制备及抗胃癌细胞生长活性研究
引用本文:王和平,张和平,李立民,苏秀兰,闫晓虹.发酵乳中多糖的制备及抗胃癌细胞生长活性研究[J].内蒙古农业大学学报(自然科学版),1996(3).
作者姓名:王和平  张和平  李立民  苏秀兰  闫晓虹
作者单位:内蒙古农牧学院生物工程系,内蒙古农牧学院食品工程系,内蒙古医学院中心实验室
摘    要:本研究采用生物化学技术,提取、纯化,并鉴定了发酵乳中的多糖,其设计使用的制备多糖方法具有成本低、多糖纯度好、产量高的特点,并且用3H-Tdr掺入法测定了多糖抗胃癌细胞生长活性的抑制率。经研究这种发酵乳中的多糖在水中的溶解性差,但易溶解在酸性溶液中。该多糖抗胃癌细胞生长活性的抑制卒为81.44%,在发酵乳中的含量大于1250mg/L。

关 键 词:发酵乳,多糖,抗胃癌细胞生长活性

Preparation of Polysaccharide from Fermented Milkand Its Anti-Gastric Carcinoma Cell Activity
Wang Heping,Zhang Heping,Lilimin,Shu Xiulan,Yan Xiaohong.Preparation of Polysaccharide from Fermented Milkand Its Anti-Gastric Carcinoma Cell Activity[J].Journal of Inner Mongolia Agricultural University(Natural Science Edition),1996(3).
Authors:Wang Heping  Zhang Heping  Lilimin  Shu Xiulan  Yan Xiaohong
Abstract:Extraction,purification and identification of polysaccharide from fer-mentedmilk were conducted through biochemical technology.Using H-TdR incorpora-tion method,growth inhibtion of human gastric carcinoma cell induced by this polysac-charide was also studied in this research report.Our study results indicated that theamount of this polysaccharide produced in fermented milk was great(up to 125 mg/100ml)and is had significant effect on the growth of human gastric carcinoma cell,aver-age inhibition rate being 81.44%.
Keywords:active polysaccharide  fermented milk  anti-gastric carcinomal cell ac-tivity
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