| 糖耐量减低患者的转归及影响因素的Logistic多元回归分析 |
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| 引用本文： | 陈晓铭,武革,周飞,吴美芬,陈文璞.糖耐量减低患者的转归及影响因素的Logistic多元回归分析[J].湛江医学院学报,2010,28(4):374-375,383. |
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| 作者姓名： | 陈晓铭 武革 周飞 吴美芬 陈文璞 |
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| 作者单位： | 广东医学院附属医院内分泌科,广东湛江,524001 |
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| 摘 要： | 目的观察糖耐量减低（IGT）患者中糖尿病发生率及其危险因素。方法收集2005至2006年糖耐量减低患者355例，随机分为干预治疗组（n=166）和非干预治疗组（n=189），出院后随访3a，统计糖尿病（DM）发生率，用Logistic多元回归分析其危险因素。结果非干预治疗组中发生DM70例07．0％），年转化率为12．3％；干预治疗组中发生DM24例（14．4％），年转化率为4．8％；两组比较差异有统计学意义（P〈0．05）。糖尿病发病的危险因素主要与餐后2h血糖（OR=3．016）、家族史（OR=1．446）和年龄（OR=1．176）有关。结论IGT患者发生DM的主要危险因素为餐后2h血糖、家族史和年龄，早期干预可明显降低DM发生率。
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| 关 键 词： | 糖耐量减低 糖尿病 干预治疗 |
Multivariate logistic regression analysis for outcome and risk factors of impaired glucose tolerance patients |
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| CHEN Xiao-ming,WU Ge,ZHOU Fei,WU Mei-fen,CHEN Wen-pu.Multivariate logistic regression analysis for outcome and risk factors of impaired glucose tolerance patients[J].Journal of Guangdong Medical College,2010,28(4):374-375,383. |
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| Authors: | CHEN Xiao-ming WU Ge ZHOU Fei WU Mei-fen CHEN Wen-pu |
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| Institution: | (Department of Endocrinology, Affiliated Hospital of Guangdong Medical College, Zhanjiang 524001, China) |
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| Abstract: | Objective To observe the incidence and risk factors of diabetes mellitus （DM） in patients with impaired glucose tolerance （IGT）. Methods A total of 355 IGT patients enrolled from 2005 to 2006 were randomly divided into control group （n=189） and treatment group （n=166）, and the incidence and risk factors of DM in both groups were analyzed by multivariate logistic regres-sion an- alysis within 3-year followed-up. Results The incidence and annual conversion rate of DM were 37.0% and 12.3% in control group, and 14.4% and 4.8% in treatment group, respectively; there were statistical differences between both groups （P〈0.05）. The risk factors of DM were 2h blood glucose （OR=3.016）, diabetes family history （OR=1.446） and age （OR=1.176）. Conclusion The risk factors of DM include 2h blood glucose, diabetes family history and age, and early intervention may improve the prevalence of DM in IGT patients. |
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| Keywords: | impaired glucose tolerance diabetes mellitus intervention |
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