CLINICAL VALUE OF FRUCTOSAMINE MEASUREMENTS AND FRUCTOSAMINE-ALBUMIN RATIO IN HYPOGLYCEMIC FERRETS (MUSTELA PUTORIUS FURO) |
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| Authors: | Alexis Duhamelle Frederic Vlaemynck Elodie Loeuillet Sylvain Larrat |
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| Institution: | 1. Exotic Pet Medicine Service, Clinique Vétérinaire Alliance, Bordeaux, France;2. Clinique Caduvet Lille, Loos, France;3. Refuge des Ch’tis Furets, Brech, France;4. Exotic Pet Medicine Service, Clinique Vétérinaire Benjamin Franklin, Brech, France |
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| Abstract: | The objective of this preliminary study was to establish a reference range for plasma fructosamine concentration and fructosamine-albumin ratio in healthy ferrets and to compare these reference intervals to values obtained from hypoglycemic ferrets. Fructosamine concentration has been shown to reflect blood glucose concentration over the previous 1 to 2 weeks in other animal species, and may be a useful indicator of chronic hypoglycemia in ferrets diagnosed with insulinoma. Plasma fructosamine was measured with an automated colorimetric assay using nitroblue tetrazolium. Thirty-two clinically healthy and 5 hypoglycemic ferrets were included in the study. The reference interval in healthy ferrets for fructosamine was 110 (98 to 123) – 203 (191 to 218) μmol/L, and the reference interval for plasma fructosamine-albumin ratio was 5.1 (4.6 to 5.6) – 8.6 (8.2 to 9.0) μmol/g. Results for hypoglycemic ferrets were within the ranges for both fructosamine and fructosamine-albumin ratio. As there were no significant differences between the healthy and hypoglycemic ferrets, this study suggests that fructosamine concentration and fructosamine-albumin ratio are not likely to be useful in determining insulinoma-associated chronic hypoglycemia in ferrets. |
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| Keywords: | ferret fructosamine albumin insulinoma hypoglycemia |
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