| 鸡喹乙醇中毒对血中自由基水平及抗氧化系统的影响 |
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| 引用本文： | 高洪,浦雪艳,彭辂,彭洁.鸡喹乙醇中毒对血中自由基水平及抗氧化系统的影响[J].云南农业大学学报,2007,22(3):396-400. |
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| 作者姓名： | 高洪 浦雪艳 彭辂 彭洁 |
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| 作者单位： | [1]云南农业大学,云南昆明650201 [2]上海开拓者生物科技发展有限公司,上海浦东201203 [3]四川大学,四川成都610064 |
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| 基金项目： | 云南省自然科学基金资助（2003C0049M）. |
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| 摘 要： | 对鸡喹乙醇中毒时，血中自由基（MDA）及抗氧化系统的变化进行了研究；艾维因鸡随机分为两组，正常对照组（Ⅰ组），饲喂基础日粮；喹乙醇处理组（Ⅱ组），饲喂基础日粮，且以15 mg喹乙醇/kg体重处理Ⅱ组，连续处理42 d，每天1次，Ⅰ，Ⅱ组每7 d采血1次，共采血6次，测定MDA及抗氧化系统各指标水平；结果：第2～6次Ⅱ组MDA水平明显高于Ⅰ组（P<0.05，P<0.01），而Ⅱ组T-AOC,GSH,T-SOD,CAT,GST,GSH-PX水平明显低于Ⅰ组（P<0.05，P<0.01）。第1次各指标在Ⅰ，Ⅱ组间无显著性差异（P＞0.05）。鸡喹乙醇中毒时可引起血中自由基水平（MDA）明显升高，而抗氧化系统各指标水平明显下降。
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| 关 键 词： | 鸡 喹乙醇中毒 自由基 抗氧化酶 影响 |
| 文章编号： | 1004-390X（2007）03-0396-05 |
| 收稿时间： | 2006-11-3 |
| 修稿时间： | 2006-11-03 |
The Effect of Olaquindox Poisioing on Free Radical and Anti-oxidative System in Chicken Blood |
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| GAO Hong,PU Xue-yan,PENG Lu,PENG Jie.The Effect of Olaquindox Poisioing on Free Radical and Anti-oxidative System in Chicken Blood[J].Journal of Yunnan Agricultural University,2007,22(3):396-400. |
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| Authors: | GAO Hong PU Xue-yan PENG Lu PENG Jie |
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| Institution: | 1. Yunnan Agriuchural University, Kunming 650201 ,China; 2. Shanghai Bioexplorer Co. , Ltd. , Shanghai 201203, China; 3. Sichuan University, Chendu 610064, China |
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| Abstract: | The changes of free radical （malondialdehyde, MDA） and anti-oxidative system in chicken blood during olaquindox poisoning were achieved. Aiweiyin chickens were divided randomly into 2 groups: the chickens of Control group （groupⅠ） were only fed on basic diet, and those of olaquindox -treated group （group Ⅱ） were administrated by 15 micrograms olaquindox per kilogram body weight besides being fed on basic diet, olaquindox was orally given once per day with total times, blood was sampled 6 times with once per 7 days for detection of MDA and anti-oxidative indexes. At the 2nd to 6th detection, MDA of group Ⅱ was significantly higher than that of groupⅠ（P<0.05，P<0.01）,and all anti-oxidative indexes （T-AOC,GSH,T-SOD,CAT,GST,GSH-PX） of group Ⅱ were remarkably lower than those of group Ⅰ（P<0.05，P<0.01, no differences existed in groupⅠ and group Ⅱat the 1st detection （P＞0.05）. Chicken olaquindox poisoning can results in remarkable increase of blood MDA and significant decrease of anti-oxidation indexes. |
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| Keywords: | Chicken olaquindox poisoning free radical antioxidase effect |
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