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| 狂犬病实验室诊断研究进展 | |
| 引用本文： | 高明华,张志琰,沈为明,韩启茂.狂犬病实验室诊断研究进展[J].动物医学进展,2008,29(4):70-75. |
| 作者姓名： | 高明华 张志琰 沈为明 韩启茂 |
| 作者单位： | 1. 呼伦贝尔学院生命科学与化学学院,内蒙古海拉尔,021008 2. 扎兰资迅中心,内蒙古扎兰屯,162650 3. 阿荣旗动物防疫监督所,内蒙古阿荣旗,162750 |
| 基金项目： | 国家科技部攻关计划课题 |
| 摘 要： | 狂犬病是世界上最可怕的人兽共患传染病,所有温血动物对狂犬病均易感,狂犬病已成为世界严重的公共卫生问题。暴露后疫苗接种可以达到有效的预防,狂犬病的预防和暴露后处理措施的有效实施均有赖于实验室的安全、准确、快速诊断。另外,免疫后及时对血清中和抗体效价进行监测,也是防控狂犬病的关键措施。文章从狂犬病实验室诊断的安全问题、实验室检测样本的选择、组织学检查、病毒抗原检测、生物学鉴定、核酸检测及血清抗体检测等方面对狂犬病实验室诊断方法及研究进展等进行综述和评价。 |
| 关 键 词： | 狂犬病 实验室诊断 抗原 核酸 血清学 |
| 文章编号： | 1007-5038(2008)04-0070-06 |
| 修稿时间： | 2008年1月4日 |
Advance in the Laboratory Diagnosis on Rabies |
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| GAO Ming-hua,ZHANG Zhi-yan,SHEN Wei-ming,HAN Qi-mao.Advance in the Laboratory Diagnosis on Rabies[J].Progress In Veterinary Medicine,2008,29(4):70-75. | |
| Authors: | GAO Ming-hua ZHANG Zhi-yan SHEN Wei-ming HAN Qi-mao |
| Abstract: | Rabies is one of the most feared zoonotic diseases that is considered to be a serious public health problem in the world.All warm-blooded animals are susceptible to infection by the virus.Rabies can be prevented by post exposure vaccination.However,the effective use of post exposure vaccination depends on the safe,rapid and accurate detection of rabies virus in specimens obtained from the source of human infection.Meanwhile,the immunologic surveillance of neutralizing antibody after vaccination is also a key preventive measure.This paper provided an overview on developments on laboratory methods for the detection of rabies at safe consideration of laboratory diagnoses,selection of samples,histopathology,detection of antigens,bioassays,detection of nucleic acids and serological tests. |
| Keywords: | Rabies laboratory diagnosis antigen nucleicacid serology |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |