Induction of larval metamorphosis in the sea cucumber Apostichopus japonicus by neurotransmitters |
| |
| Authors: | Hiroshi Matsuura Ikuko Yazaki and Tatsufumi Okino |
| |
| Institution: | (1) Graduate School of Environmental Science, Hokkaido University, Sapporo 060-0810, Japan;(2) Department of Biology, Tokyo Metropolitan University, Tokyo 192-0397, Japan;(3) Faculty of Environmental Earth Science, Hokkaido University, Sapporo 060-0810, Japan |
| |
| Abstract: | Larval metamorphosis inducers of the sea cucumber Apostichopus japonicus were screened from physiologically active compounds. Doliolaria larvae completed their metamorphosis to juveniles in 120 h
when treated with 5–10 μM of dopamine and l-DOPA, and 50 μM of l-adrenaline and l-noradrenaline. Doliolaria larvae had to be exposed to dopamine or l-DOPA for at least 24 h. D1-like dopamine receptor antagonists SKF87566 and LE300 (10 μM) inhibited metamorphosis by dopamine.
However, the D2-like dopamine receptor antagonists sulpiride and nemonapride (10 μM) did not inhibit the effect of dopamine.
The results suggest that D1-like dopamine receptors are involved in larval metamorphosis of the sea cucumber A. japonicus. |
| |
| Keywords: | Doliolaria larva Dopamine l-DOPA" target="_blank">l-DOPA Metamorphosis Pentactula larva |
| 本文献已被 SpringerLink 等数据库收录！ |
|
