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Protection of lambs with a purified metabolite of exsheathed third-stage Haemonchus contortus larvae |
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| Authors: | R J Boisvenue R B Galloway J C Hendrix |
| Abstract: | Helminth-free lambs (approx 4 months old) were inoculated SC with a purified metabolite of exsheathed third-stage Haemonchus contortus larvae. The metabolite was obtained from in vitro cultivation and was identified as XL3FA1. After 3 periodic XL3FA1 inoculations, lambs were challenge exposed with H contortus. Multiple vaccinations with XL3FA1 did not inhibit the development of worm populations in the lambs; however, worm egg production seemed to be inhibited. |
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