Comparative susceptibility of indigenous and improved pig breeds to Classical swine fever virus infection: Practical and epidemiological implications in a subsistence-based, developing country setting |
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| Authors: | S D Blacksell S Khounsy D Van Aken L J Gleeson H A Westbury |
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| Institution: | (1) CSIRO Australian Animal Health Laboratory, Geelong, Victoria, Australia;(2) Department of Microbiology and Parasitology, University of Queensland, St Lucia, Brisbane, Queensland, Australia;(3) Department of Livestock and Fisheries, Ministry of Agriculture and Forestry, Vientiane, Lao People’s Democratic Republic;(4) European Union Strengthening Livestock Services Project, Vientiane, Lao People’s Democratic Republic |
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| Abstract: | This study investigated the comparative susceptibility of indigenous Moo Laat and improved Large White/Landrace pig breeds to infection with classical swine fever virus (CSFV) under controlled conditions
in the Lao People’s Democratic Republic (Lao PDR). The Moo Laat (ML) and Large White/Landrace crossbreed (LWC) pigs were inoculated with a standard challenge strain designated Lao/Kham225 (infectivity titre of 102.75 TCID50/ml). The results demonstrated that both the native breed and an improved pig breed are fully susceptible to CSFV infection
and the mortality rate is high. LWC pigs demonstrated lower (or shorter) survival times (50% survival time: 11 days), earlier
and higher pyrexia and earlier onset of viraemia compared to ML pigs (50% survival time: 18 days). In the context of village-based
pig production, the longer time from infection to death in native ML pigs means that incubating or early sick pigs are likely
to be sold once an outbreak of CSF is recognized in a village. This increased longevity probably contributes to the maintenance
and spread of disease in a population where generally the contact rate is low. |
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| Keywords: | Classical swine fever Laos Asia Smallholder Native breed Comparative susceptibility |
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