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A new flavonoid glycoside from the leaf of Cephalotaxus koreana |
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| Authors: | Bae Kihwan Jin Wenyi Thuong Phuong Thien Min Byung Sun Na Minkyun Lee Young Mi Kang Sam Sik |
| Institution: | College of Pharmacy, Chungnam National University, Daejeon, South Korea. baekh@cnu.ac.kr |
| Abstract: | A new flavone glycoside, apigenin 5-O-alpha-L-rhamnopyranosyl-(1-->3)-beta-D-glucopyranoside (1), along with four known flavonol glycosides (2-5), were isolated from the leaf of Cephalotaxus koreana. The new glycoside 1 showed inhibitory activity in superoxide radical scavenging assay with IC(50) value of 13.0 microM, while it showed weak activity in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay. Compounds 2-5 exhibited antioxidant activity in scavenging DPPH and superoxide radicals with IC(50) values ranging from 5.7 to 22.3 microM. |
| Keywords: | Cephalotaxus koreana Apigenin 5-O-α-l-rhamnopyranosyl-(1 → 3)-β-d-glucopyranoside Antioxidant activity |
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