Functional rice giant embryo and Aranghyangchal reduce blood glucose level and enhance antioxidative defense status in high fat-fed mice |
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| Authors: | Mi Young Kang Soo Im Chung Mingze Xu Sang Chul Lee |
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| Institution: | 1. Department of Food Science and Nutrition, Brain Korea 21 Plus, Kyungpook National University, Daegu, 702-701, Republic of Korea
2. Division of Plant Biosciences, Kyungpook National University, Daegu, 702-701, Republic of Korea
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| Abstract: | The effect of functional rice giant embryo and Aranghyangchal on the glucose metabolism and antioxidative defense status in high fat-fed C57BL/6N mice were investigated. The animals were randomly divided into four dietary groups: normal control (NC), high fat (HF), and high fat supplemented with giant embryo rice (HF-GE) or Aranghyangchal rice (HF-AR). After 8 weeks of feeding them with experimental diets, the HF mice exhibited a marked increase in the blood glucose concentration, plasma insulin level, and lipid peroxidation and a significant decrease in the hepatic glycogen level relative to the NC group. On the other hand, diet supplementation of the rice samples suppressed this high fat diet-induced hyperglycemia and oxidative stress through inhibition of the glucose-regulating enzymes and activation of the antioxidant enzymes. These findings demonstrate that the giant embryo and Aranghyangchal rice may be beneficial as biomaterials in the development of functional food with hypoglycemic and antioxidative properties. |
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