EVALUATION OF THE POTENTIAL OF SYSTEMIC SLOW RELEASE CHEMICAL TREATMENTS FOR CONTROL OF THE CATTLE TICK
(BOOPHILUS MICROPLUS)
USING IVERMECTIN |
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| Authors: | J Nolan H J Schnitzerling P Bird |
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| Institution: | CSIRO Division of Entomology, Long Pocket Laboratories, Private Bag No. 3, Indooroopilly, Queensland, 4068 |
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| Abstract: | SUMMARY Stall and field trials with cattle infested with various acaricide-resistant strains of cattle tick, have demonstrated the potential of ivermectin as a systemic tickicide. A dosage of 200 μg/kg, administered subcutaneously to animals naturally infested in the field, gave satisfactory tick control for 21 days, after an initial lag period of 2 days immediately following treatment, during which significant numbers of ticks survived. Daily subcutaneous treatments, administered so as to simulate slow release, indicated that a dosage of 15 μg/skg/day should give complete tick control if the chemical could be released continuously from a subcutaneous implant. The potency of ivermectin, assessed by in vitro tests against engorged adults, suggests that the tickicidal activity could be associated with the parent compound per se rather than a metabolite. |
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