Bilateral intraocular glandular choristomas in a Thoroughbred foal |
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| Authors: | Wes A Baumgartner Eric S Storey† Daniel B Paulsen |
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| Institution: | Louisiana State University School of Veterinary Medicine, Department of Pathobiological Sciences, Skip Bertman Dr., Baton Rouge, LA 70803, USA;;Louisiana State University School of Veterinary Medicine, Department of Veterinary Clinical Sciences, Skip Bertman Dr., Baton Rouge, LA 70803, USA |
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| Abstract: | Intraocular choristomas are rare anomalies in domestic animals and are often associated with multiple ocular malformations. A Thoroughbred foal presented for ocular abnormalities and was diagnosed with microphthalmia, corneal dermoids, severe anterior segment dysgenesis (including glandular choristomas), aphakia, retinal dysplasia, and optic nerve hypoplasia. Morphological, histochemical, and immunohistochemical comparisons were made between ocular choristomatous tissues from this foal and lacrimal gland, third eyelid gland, nasopharynx, trachea, and lacrimal sac/nasolacrimal duct from normal horses. Morphologically the choristomatous tissues (glands and epithelium lining the anterior segment) were most similar to the lacrimal sac. Histochemistry of glandular components found the glands associated with the lacrimal sac/nasolacrimal duct to be serous, as was the glandular intraocular choristomas. Our findings suggest that the origin of intraocular glandular choristomas in this case is from the lacrimal sac. |
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| Keywords: | anterior segment dysgenesis Equus caballus horse intraocular choristoma lacrimal sac microphthalmia |
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