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Salivary Gland Adenocarcinoma in a Domestic Rabbit (Oryctolagus cuniculus)
Authors:Marjorie Bercier  David Sanchez-Migallon Guzman  Jonathan Stockman  Allison Zwingenberger  Natalia Vapniarsky  Linda Lowenstine  Michelle G Hawkins
Institution:1. William M. Pritchard Veterinary Medical Teaching Hospital;2. Department of Medicine and Epidemiology;3. Department of Surgical and Radiologic Sciences;4. Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California Davis, Davis, CA USA;1. Department of Veterinary Clinics, University of Pisa, San Piero a Grado Pisa, Italy;2. Veterinary Clinic Roma Sud, Roma, Italy;3. CVS Centro Veterinario Specialistico, Perugia, Italy;4. Department of Pathology and Animal Health, Faculty of Veterinary Medicine, University of Naples Federico II, Naples, Italy;1. Lakeside Veterinary Center, LLC, Laurel, MD USA;2. The Veterinary Pathology Service, Joint Pathology Center, Silver Spring, MD USA;1. Exotic Animal and Wildlife Service, The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush Veterinary Centre, Midlothian, UK;2. Chester Zoo, Chester, UK;3. Department of Veterinary Science Small Animal Teaching Hospital, University of Liverpool, Neston, UK;4. Veterinary Pathology, School of Veterinary Sciences, University of Bristol, Langford, UK
Abstract:A 2.4 kg, 7-year-old, female Rex rabbit was presented with a 4-month history of a left-sided head tilt, difficulty in mastication, lethargy, and chronic wasting. Diagnostic testing of the patient revealed a severe heterophilic leukocytosis and radiographic images of the skull radiographs indicated irregularity of the left tympanic bulla. A computed tomographic scan highlighted a heterogeneously contrast-enhancing mass, ventral and rostral to the left tympanic bulla, with contrast enhancement of the meninges on the left, consistent with an aggressive neoplasm. The patient was euthanized and the mass was identified as a salivary gland adenocarcinoma. The gland of origin is suspected to be the left parotid, owing to its location and close association with normal parotid tissue. To the authors' knowledge, this is the first report of a salivary gland adenocarcinoma in a domestic rabbit. A computed tomography (CT) scan and histopathology examination were useful modalities for identifying the neoplasm in this case.
Keywords:adenocarcinoma  parotid gland  rabbit  salivary gland
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