| 饲料添加砷制剂对小鼠铁吸收的影响 |
| |
| 引用本文： | 何万领,李晓丽,李元晓,李旺,杨自军.饲料添加砷制剂对小鼠铁吸收的影响[J].兽医大学学报,2014(2):328-330. |
| |
| 作者姓名： | 何万领 李晓丽 李元晓 李旺 杨自军 |
| |
| 作者单位： | 河南科技大学动物科技学院环境与畜产品安全河南省重点实验室,河南洛阳471003 |
| |
| 基金项目： | 河南科技大学博士启动基金资助项目（09001406）;河南省教育厅自然科学基金资助项目（2010B230001）;国家自然科学基金资助项目（31040081） |
| |
| 摘 要： | 为探讨饲料中添加砷制剂对小鼠铁吸收的影响，45只小鼠被随机分为3组，各组在基础日粮中分别添加0，40，80mg／kg砷（以洛克沙胂形式），试验期30d。试验结束后，收取各组粪便和组织器官测定铁含量。结果显示，与对照组相比，40mg／kg砷组铁表观吸收率提高14．57％，80mg／kg砷组铁表观吸收率则降低了14．93％；40mg／kg砷组小鼠肝脏、肾脏、脾脏、小肠和腿肌铁含量显著升高（P〈O．05），80mg／kg砷组则显著降低（P〈O．05）；但两组分别于停砷后5，7d，组织器官铁恢复正常水平。这表明40mg／kg砷水平可促进铁的吸收，相反80mg／kg砷水平则抑制铁的吸收。
|
| 关 键 词： | 小鼠 洛克沙胂 铁吸收 |
Effects of diet supplement roxarsone on iron absorption in mice |
| |
| Authors: | HE Wan-ling LI Xiao-li LI Yuan-xiao LI Wang YANG Zi-jun |
| |
| Institution: | (Province of Henan Key Laboratory of Environment and Safety of Animal Products, College of Animal Science and Technology, Henan University of Science and Technology ,Luoyang, Henan 471003 ,China) |
| |
| Abstract: | To explore the effects of arsenate on iron absorption in mice, forty-five mice were ran domly divided into 3 groups which were fed on basal diet supplemented with 0,40,and 80 mg/kg roxarsone （ROX） respectively. Thirty days later,feces and tissue samples of each group were col lected. Compared with the control group,the group fed with 40 mg/kg ROX increased by 14.57o/4o of iron apparent absorption;in opposition,the iron apparent absorption rate decreased by 14.93% when treated with 80 mg/kg ROX. Iron contents of liver,kidney,spleen,intestine,and thigh mus-cle were significantly increased as treated with 40 mg/kg ROX; in opposition, iron contents of those were significantly decreased as treated with 80 mg/kg ROX. However, iron contents of or-ganic tissues in both groups returned to normal levels at 5 or 7 days after withdraw ROX. Diet supplemented with 40 mg/kg ROX can enhance iron absorption,while 80 mg/kg ROX can reduce iron absorption. |
| |
| Keywords: | mice ROX iron absorption |
| 本文献已被 维普 等数据库收录！ |
|
