| 饮茶对镉染毒SD大鼠抗氧化和脂质代谢的影晌 |
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| 引用本文： | 陈小洁,李晓丽,何万领.饮茶对镉染毒SD大鼠抗氧化和脂质代谢的影晌[J].兽医大学学报,2014(2):319-322. |
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| 作者姓名： | 陈小洁 李晓丽 何万领 |
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| 作者单位： | [1]河南科技大学动物科技学院,河南洛阳471003 [2]河南师范大学生命科学院,河南新乡453000 |
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| 基金项目： | 河南科技大学博士基金资助项目（09001406）;河南省教育厅自然科学基金资助项目（20108230001）;国家自然科学基金资助项目（20677051） |
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| 摘 要： | 选用体质量均匀的成年雌、雄SD大鼠，并分为对照组、镉染毒组和镉染毒饮茶干扰组。在饲喂基础日粮的基础上，对照组饮用自来水；镉染毒纽饮用含镉（60mg／L）的水；镉染毒饮荼干扰组饮用舍镉（60mg／L）的龙井茶，探讨饮茶对镉毒性的干预效果。结果表明，镉可造成细胞脂质过氧化，细胞抗氧化能力降低，影响细胞正常代谢，并可导致机体血脂升高、动脉硬化的几率增加。饮茶拮抗镉的脂质过氧化损伤，激活了体内的抗氧化防御系统，并可降血脂、预防动脉硬化及调节脂质代谢。
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| 关 键 词： | SD大鼠 饮茶 镉 抗氧化指标 脂质代谢 |
Impact of tea on antioxidant and lipid metabolism in SD rats exposed to cadmium |
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| Authors: | CHEN Xiao-jie LI Xiao-li HE Wan-ling |
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| Institution: | 1. College of Animal Science and Technology, Henan University of Science and Technology ,Luoyang, Henan 471003, China;2. School of Life Sciences, Henan Norm al University, Xinliang, Henan 453000, China) |
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| Abstract: | The adult male and female SD rats were used in the experiment,which were divided into three groups,the control group drunk tap water; the cadmium group drunk containing cadmium （60 mg/L） of water; the Longjing tea intervention group drunk water containing cadmium 60 mg/L,to study the intervention effect of tea on cadmium toxicity. The results showed that, high cadmium can cause cell lipid peroxidation,reduce antioxidant capacity,affect the normal metabolism of cells and may lead to increase blood lipids and the risk of atherosclerosis. Tea antagonism to cadmium can activate the body＇s antioxidant defense system and reduce blood pressure,and can prevent arte-riosclerosis and regulate lipid metabolism. |
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| Keywords: | SD rats drink tea cadmium antioxidant index lipid metabolism |
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