| 猪流行性腹泻病毒实验感染猪血清抗体的消长规律 |
| |
| 引用本文： | 谢明星,朱维正.猪流行性腹泻病毒实验感染猪血清抗体的消长规律[J].中国兽医学报,1988(2). |
| |
| 作者姓名： | 谢明星 朱维正 |
| |
| 作者单位： | 兽医大学传染病教研室
(谢明星)，兽医大学传染病教研室(朱维正) |
| |
| 摘 要： | 应用微量中和试验(MT)、间接血凝试验(IHA)和间接酶联免疫吸附试验(间接ELISA)对三种不同途径即滴鼻、口服和肌肉注射人工感染猪流行性腹泻病毒的12头仔猪的血清抗体进行了检测。感染猪在第1～2周时即可测出抗体,3～5周后抗体滴度达高峰,抗体持续时间最短为18周,最长可达22周以上。其中以肌注和滴鼻组抗体产生较早,而口服组稍晚。肌注组抗体上升较快,抗体持续时间较短,而滴鼻和口服组抗体上升稍慢,抗体持续时间较长。
|
| 关 键 词： | 猪流行性腹泻 抗体消长规律 微量中和试验 间接血凝试验 间接酶联免疫吸附试验 |
Serum Antibody Changes of Pigs Experimentally Infected with Porcine Epizootic Diarrhea Virus (PEDV) |
| |
| Xie Mingxing et al..Serum Antibody Changes of Pigs Experimentally Infected with Porcine Epizootic Diarrhea Virus (PEDV)[J].Chinese Journal of Veterinary Science,1988(2). |
| |
| Authors: | Xie Mingxing |
| |
| Abstract: | Microtiter neutralization test, indirect hemagglutination assay and indirect enzyme-linked immunosorbent assay were applied to determine the changes of serun antibodies in twelve pigs experimentally infected with PED virus by oral, intramuscular or intranasal routes. Serum antibodies in inoculated pigs were detected from 1-2 weeks after exposure to the virus and the titer of which reached a peak in 3-5 weeks after infection. The antibody to PEDV persisted for at least 18-22 weeks. Serum antibody in intramuscularlly (i.m.) and intranasally (i.n.) infected pigs could be detected earlier than in orally infected piges. Serum titers in i.m. pigs increased slightly faster but lasted a bit shorter, however serum titers in i.n.and orally-infected pigs increased slightly slower but persisted a bit longer. |
| |
| Keywords: | PED serum antibody changes microtiter neutralization test indirect hemagglutination assay indirect enzyme linked immunosorbent assay |
| 本文献已被 CNKI 等数据库收录！ |
