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Antimutagenic, antioxidant and antimicrobial properties of Maytenus krukovii bark |
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| Authors: | Bruni Renato Rossi Damiano Muzzoli Mariavittoria Romagnoli Carlo Paganetto Guglielmo Besco Elena Choquecillo Fritz Peralta Katia Lora William Schmitt Sacchetti Gianni |
| Institution: | Dipartimento di Biologia Evolutiva e Funzionale, Parco Area delle Scienze 11, 43100 Parma, Italy. bruni@biol.unipr.it |
| Abstract: | The hydroalcoholic extract of Maytenus krukovii bark was investigated for its in vitro mutageno-protective activities by means of the Ames Salmonella/microsome assay. The extract showed an inhibitory effect in both T98 and T100 strains against the mutagenic activity of promutagen 2-aminoanthracene but was not protective against directly acting mutagens sodium azide and 2-nitrofluorene. When tested as a radical scavenger and antioxidant it produced a dose-dependent inhibition. The extract did not show significant antibacterial properties, and was weakly active against dermatophyte and phytopathogenic fungi, but inhibited the growth of phytopathogen Pithyum ultimum. |
| Keywords: | Maytenus krukovii Antimutagenicity Antioxidant activity Antimicrobial activity |
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