| 川芎和黄芪对大鼠妊娠期高血压疾病的影响 |
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| 引用本文： | 杨敏,邹杰晶.川芎和黄芪对大鼠妊娠期高血压疾病的影响[J].黑龙江农业科学,2014(12):82-85. |
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| 作者姓名： | 杨敏 邹杰晶 |
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| 作者单位： | 1. 吉林农业科技学院,吉林吉林,132001
2. 吉林医药学院附属医院,吉林吉林,132001 |
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| 基金项目： | 吉林农业科技学院青年基金资助项目(吉农院合字[2013]第222号) |
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| 摘 要： | 为了进一步开发利用川芎和黄芪,以受孕大鼠为试材,观察川芎、黄芪对大肠杆菌内毒素致妊娠高血压综合征(妊高征)大鼠血压、尿蛋白及胎盘、胎仔发育情况的影响。结果表明:与正常妊娠组比较,妊高征模型对照组尿蛋白和血压水平明显升高,说明造模成功。川芎和黄芪组与模型对照组比较,尿蛋白和血压均降低,硫酸镁阳性对照组血压比模型对照组低,尿蛋白略有下降,但差异无统计学意义。川芎和黄芪组死胎率较模型对照组明显降低,畸胎率亦显著下降。川芎、黄芪能够有效降低妊高征大鼠血压和尿蛋白,促进妊高征大鼠胎盘供血和胚胎发育。
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| 关 键 词： | 妊娠高血压 大鼠 内毒素 硫酸镁 川芎 黄芪 |
Effect of Ligustici and Astragalus on Gestational Hypertension of Rat |
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| YANG Min
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ZOU Jie-jing.Effect of Ligustici and Astragalus on Gestational Hypertension of Rat[J].Heilongjiang Agricultural Science,2014(12):82-85. |
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| Authors: | YANG Min ZOU Jie-jing |
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| Institution: | YANG Min , ZOU Jie-jing ( 1. College of Agricultural Science and Technology ,Jilin,Jilin 132001 ; 2. Jilin Medical School Affiliated Hospital,Jilin,Jilin 132001) |
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| Abstract: | For further development and utilization of ligustici and Astragalus,taking ingravidation rats as experimental material,the effect of ligustici and Astragalus on blood pressure,urine protein and development situation of placenta and fetal rat with pregnaney indueed hypertension syndrome rats was observe.The results showed that compared with normal pregnancy group（group A）,urine protein,blood pressure levels of model control group（group B）increased significantly,therefore the building was successful.Compared with group B,urine protein,blood pressure of ligustici and Astragalus group（group D）were lower,blood pressure of positive control group（group C）was lower,urine protein of group C declined slightly,but there was no statistically significant difference.Stillbirth rate of Group D was significantly lower than group B,teras rate also declined significantly.The ligustici and Astragalus could effectively reduce the blood pressure and the urine protein of pregnaney indueed hypertension rats,and promoted placental blood flow and embryonic development of rats. |
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| Keywords: | pregnaney indueed hypertension rat endotoxin magnesium sulfate ligustici Astragalus |
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