| 不同动物肠道微生物对黄豆苷原的转化研究 |
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| 引用本文： | 王秀伶,邵建柱,朱宝成,袁洪水,王世英.不同动物肠道微生物对黄豆苷原的转化研究[J].河北农业大学学报,2007,30(1):79-83. |
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| 作者姓名： | 王秀伶 邵建柱 朱宝成 袁洪水 王世英 |
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| 作者单位： | 1. 河北农业大学,生命科学学院,河北,保定,071001
2. 河北农业大学,园艺学院,河北,保定,071001 |
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| 基金项目： | 国家自然科学基金(30570035)，河北农业大学归国留学人员科研启动基金项目资助 |
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| 摘 要： | 采用高效液相色谱技术,分析比较了32种不同动物肠道微生物菌群对黄豆苷原的转化情况。在全部供试动物中,只有大熊猫的肠道微生物菌群对黄豆苷原未表现转化能力,其余31种动物的代谢产物中均出现了去氧甲基安哥拉紫檀素;有14种动物对黄豆苷原的代谢产物中出现了高活性植物雌激素雌马酚。研究表明,不同动物对黄豆苷原的代谢能力强弱不仅与遗传因素有关,同时还与动物本身的饮食结构等环境因素有关。通过测定黄豆苷原在不同动物体内的代谢产物,确定了一些对黄豆苷原具有较强代谢能力的动物种类,尤其是确定了一些能将黄豆苷原高效转化为雌马酚的理想动物种类。
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| 关 键 词： | 黄豆苷原 肠道微生物 生物转化 高效液相色谱 |
| 文章编号： | 1000-1573(2007)01-0079-05 |
| 修稿时间： | 2006年11月2日 |
Biodegradation of isoflavone daidzein by intestinal microbes in different animals |
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| WANG Xiu-ling,SHAO Jian-zhu,ZHU Bao-cheng,YUAN Hong-shui,WANG Shi-ying.Biodegradation of isoflavone daidzein by intestinal microbes in different animals[J].Journal of Agricultural University of Hebei,2007,30(1):79-83. |
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| Authors: | WANG Xiu-ling SHAO Jian-zhu ZHU Bao-cheng YUAN Hong-shui WANG Shi-ying |
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| Abstract: | Biodegradation capacity of daidzein by intestinal microflora from thirty-two different animals were compared by High Performance Liquid Chromatography(HPLC).The results showed that all of the other thirty-one tested animals converted daidzein into O-desmethylangolensin(O-Dma) except the giant panda.Fourteen tested animals were detected with the ability to produce phytoestrogen equol with high physiological activities in their daidzein metabolites.The results indicated that different daidzein bioconverting capacity is influenced by genetic factors.Meanwhile,it is also related to some environmental factors like diet arrangement.Taken together,some special animals with strong daidzein biodegradation capacity,especially those ideal animals that can convert daidzein into equol efficiently,were determined by detecting daidzein metabolites produced in different animals. |
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| Keywords: | daidzein intestinal microflora biodegradation HPLC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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