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| 亚临床酮病对围产期奶牛免疫功能的影响 | |
| 引用本文： | 薛俊欣,缪德年,黄克和,张克春.亚临床酮病对围产期奶牛免疫功能的影响[J].上海交通大学学报(农业科学版),2011,29(1):48-53. |
| 作者姓名： | 薛俊欣 缪德年 黄克和 张克春 |
| 作者单位： | 1. 南京农业大学,动物医学院,南京,210095 2. 上海市农业科学院,畜牧所,上海,201106 3. 南京农业大学,动物医学院,南京,210095;上海市奶牛研究所,上海,200436 |
| 基金项目： | 科技部十一五支撑计划项目奶牛专项; 公益性行业(农业)科研专项(nyhyzx07-036-02); |
| 摘 要： | 从43头荷斯坦奶牛(体细胞数＜200 000个·mL-1)中筛选出处于分娩第14天的自然发生亚临床酮病的9头奶牛作为试验组(1.0 mmol·L-1≤血清β-羟丁酸＜2.6 mmol·L-1),根据泌乳天数、年龄、胎次、产奶量配对的9头健康奶牛作为对照组(血液β-羟丁酸＜1.0 mmol·L1),检测不同种类白细胞数量... |
| 关 键 词： | 奶牛 亚临床酮病 免疫功能 白细胞 细胞因子 |
Influence of Sub-Clinical Ketosis on Immunological Function of Dairy Cows During Peripartum |
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| XUE Jun-xin,MIAO De-nian,HUANG Ke-he,ZHANG Ke-chun.Influence of Sub-Clinical Ketosis on Immunological Function of Dairy Cows During Peripartum[J].Journal of Shanghai Jiaotong University (Agricultural Science),2011,29(1):48-53. | |
| Authors: | XUE Jun-xin MIAO De-nian HUANG Ke-he ZHANG Ke-chun |
| Institution: | XUE Jun-xin1,MIAO De-nian2,HUANG Ke-he1,ZHANG Ke-chun1,3(1.College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China,2.Institute of Animal Husbandry and Veterinary Sciences,Shanghai Academy of Agricultural Sciences,Shanghai 201106,3.Shanghai Institute of Dairy Science,Shanghai 200436,China) |
| Abstract: | 9 subclinical ketosis cows that delivered in 14 days（1.0 mmol·L-1≤serum β-hydroxybutyrate 2.6 mmol·L-1） were selected as the test group from 43 Holstein cows（Somatic cell count 200 000·mL-1）.The control group（serum β-hydroxybutyrate 1.0 mmol·L-1） which contained 9 healthy cows was paired according to days in milk,age,parity and milk yield.Blood samples were collected for analysis of several kinds of white blood cell counts,phagocytosis function and chemotaxis function of neutrophils,lymphocyte transformation rate and the levels of immunoglobulin G,interleukin-2,interleukin-8 and γ-interferon in the serum.The results showed that white blood cell count,the number of neutrophils and lymphocyte,the rate of phagocytosis and the chemotactic index of neutrophils in the blood of the subclinical ketosis cows were significantly lower than that of control group（P0.05）.Lymphocyte transformation rate was significantly lower than that of control group（P0.01）.Serum level of γ-IFN was significantly lower than that of control group（P0.05）.Subclinical ketosis decreased immunological function in dairy cows. |
| Keywords: | dairy cow sub-clinical ketosis immunological function white blood cell cytokine |
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