Effects of Pouteria cambodiana extracts on in vitro immunomodulatory activity of mouse immune system |
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| Authors: | Manosroi Aranya Saraphanchotiwitthaya Aurasorn Manosroi Jiradej |
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| Institution: | Faculty of Pharmacy, Chiang Mai University, Thailand. pmpti005@chiangmai.ac.th |
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| Abstract: | Immunomodulatory activity of water and acetone extracts of stem bark of Pouteria cambodiana was examined on murine macrophage phagocytosis nitroblue tetrazolium (NBT) dye reduction and lysosomal enzyme activity] and proliferation of splenocytes and bone marrow cells by 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay with and without lipopolysaccharide (LPS) or pokeweed mitogen (PWM). Both aqueous and acetone extracts presented immunomodulatory activity without clear dose response relationship. |
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| Keywords: | Pouteria cambodiana Phagocytosis Immunomodulatory activity Proliferation |
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