Studies of maternally-acquired antibodies in the foal to equine influenza A1 and A2, and equine rhinopneumonitis |
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| Authors: | William P Higgins DVM PhD James H Gillespie VMD Douglas S Robson PhD |
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| Abstract: | Serum and colostrum were collected from 50 mares at parturition. Pre- and post-nursing serum samples were obtained from their foals. Bi-weekly serum samples were obtained from 25 of the foals for eight weeks. Hemagglutination-inhibiting (HAI) antibody titers to equine influenza viruses A1 and A2 (EIVA1 and EIVA2) and serum-neutralizing antibody titers to equine herpes virus 1 (EHV1) were measured in serum and colostrum samples. IgG levels in serum and colostrum were determined.No antibody was detected in any foal's pre-nursing serum sample. Foal post-nursing antibody and IgG levels were equivalent to those measured in their dam's sera (EHVA1 p=0.86; EHVA2 p=0.54; EHV1 p=0.91; IgG p=0.58). The half-life of maternally-acquired serum antibody in the foals was determined to be: EIVA1=28.88 days (26.4 to 31.7 days); EIVA2=29.1 days (26.7 to 32.1 days); EHV1=31.0 days (28.1 to 34.8 days). Colostrum contained antibody and IgG at levels ranging from 2 to 8 times higher (4.3 average) than those detected in the mare's serum. |
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