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Artoindonesianin L, a new prenylated flavone with cytotoxic activity from Artocarpus rotunda
Authors:Tati Suhartati  Sjamsul Arifin Achmad  Norio Aimi  Euis Holisotan Hakim  Mariko Kitajima  Hiromitsu Takayama  Koichi Takeya
Abstract:A new prenylated flavone, named artoindonesianin L (1), was isolated from Artocarpus rotunda (Hout) Panzer (Moraceae). Its structure was elucidated as on the basis of spectroscopic evidence. Along with this new compound, four known phenolic compounds were also isolated from this plant and identified as artonins M (2) and E (3), cycloartobiloxanthone (4) and artonin O (5). All these compounds showed significant cytotoxicity against murine P388 leukemia cells.
Keywords:Artocarpus rotunda  Flavones  Cytotoxicity
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