| IL-10对感染口蹄疫病毒的树突状细胞的影响 |
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| 引用本文： | 郎需龙,王兴龙,孙春辉,张付贤,卜昭阳,路浩,唐婕,党源,王英超.IL-10对感染口蹄疫病毒的树突状细胞的影响[J].中国畜牧兽医,2009,36(11):27-29. |
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| 作者姓名： | 郎需龙 王兴龙 孙春辉 张付贤 卜昭阳 路浩 唐婕 党源 王英超 |
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| 作者单位： | （军事医学科学院军事兽医研究所， 长春 130062） |
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| 摘 要： | 树突状细胞(dendritic cells，DC)是机体中重要的抗原递呈细胞，在病毒感染机体后的免疫调节过程中具有重要作用。为研究调节IL-10的分泌是否会影响DC感染病毒后的免疫反应，本研究用FMDV感染DC后发现，IL-10的分泌量可以影响DC在免疫过程中各种细胞因子的表达，故认为IL-10在口蹄疫病毒感染过程中对机体的免疫调节具有重要的影响。
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| 关 键 词： | IL-10 口蹄疫病毒 树突状细胞 |
The Effects of IL-10 on Dendritic Cells Infected by Foot-and-mouth Virus |
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| LANG Xu-long,WANG Xing-long,SUN Chun-hui,ZHANG Fu-xian,BU Zhao-yang,LU Hao,TANG Jie,DANG Yuan,WANG Ying-chao.The Effects of IL-10 on Dendritic Cells Infected by Foot-and-mouth Virus[J].China Animal Husbandry & Veterinary Medicine,2009,36(11):27-29. |
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| Authors: | LANG Xu-long WANG Xing-long SUN Chun-hui ZHANG Fu-xian BU Zhao-yang LU Hao TANG Jie DANG Yuan WANG Ying-chao |
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| Institution: | （The Military Veterinary Institute, Academy of Military Medical Sciences of PLA, Changchun 130062, China） |
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| Abstract: | Dendritic cells(DC) are the most potent antigen presenting cells(APC) of the immune system,so it has a special place in induce of immune response.We thought that IL-10 have important effects through the process of viral infection.In this research the IL-10 and IL-10 neutralizing antibody were used to regulate the immune state of DCs when they were infected by FMDVs,the results showed that IL-10 can affect the immune regulation in the course of FMDV infection. |
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| Keywords: | 1L-10 |
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