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感染IBDV雏鸡血液ANAE^+——淋巴细胞比例和IL—2水平的动态变化研究
引用本文:陈龙,殷定忠,等.感染IBDV雏鸡血液ANAE^+——淋巴细胞比例和IL—2水平的动态变化研究[J].安徽农业大学学报,1999,26(2):183-187.
作者姓名:陈龙  殷定忠
作者单位:安徽农业技术师范学院动科系
摘    要:研究了经IBD弱毒苗免疫和未免疫的30~50日龄AA鸡在感染传染性法氏囊病病毒(IBDV)后血液ANAE^ -淋巴细胞比例和白细胞介素-2(IL-2)水平动态变化。结果表明,血液ANAE^ -淋巴细胞(%)在攻毒后的头5d内未免疫攻毒鸡(A组)和免疫攻毒鸡(B组)明显下降,且A组比B组下降的更快,第5天A组明显低于未免疫未攻毒鸡(C组),B组也较C组低,C组没有明显的变化,以后A和B组均回升,但B组比A组回升的快,至28d时A和B组均达到或接近攻毒前水平,并接近或高于C组。血浆IL-2水平A和B组在IBDV攻毒后的头7d内呈逐渐下降趋势,但A组下降的更剧烈,C组无明显差异性变化,三组相比,B和C组均高于或明显高于A组,以后A组和B组逐渐回升。

关 键 词:雏鸡  IBDV  ANAE^+-淋巴细胞  传染性法化囊病

Study on Changes of Blood ANAE+-Lymphocyte Ratio and IL-2 Level in Chicken Infected with Infectious Bursal Disease Virus (IBDV)
Chen LongYin DingzhongPang XunshengZhou Shuhe.Study on Changes of Blood ANAE+-Lymphocyte Ratio and IL-2 Level in Chicken Infected with Infectious Bursal Disease Virus (IBDV)[J].Journal of Anhui Agricultural University,1999,26(2):183-187.
Authors:Chen LongYin DingzhongPang XunshengZhou Shuhe
Abstract:Changes of blood ANAE+lymphocyte (%) and IL-2 levels in both immunized and nonimmunized Arbor Acres (AA) chickens with attenuated IBDV were studied after they were infected with virulent IBDV.The results showed that Blood ANAE+lymphocyte (%) decreased significantly in both nonimmunized chickens (group A) and immunized chickens (group B) during the first 5 days of infection,and group A's reduced more quickly than group B's,while nonimmunized uninfected chickens (group C) kept a constant level,which were higher than that in group A and B.Then group A and B both began to rise,but group B rose much more rapidly than group A,and their level had recovered to normal 28 d later.Plasma IL-2 level in group A and B tended to decrease gradually,while there was no obvious change in group C.
Keywords:ChickenInfectionInfectious bursal disease virus (IBDV)ANAE+lymphocyteIL-2  
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